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Which Is The Most Popular Medical Billing Software?

In the ever-evolving world of healthcare technology, choosing the right medical billing software has become crucial for healthcare providers. With a plethora of options available, it can be overwhelming to determine which software is truly the most popular and effective in streamlining and optimizing the complex billing process. This article aims to provide a comprehensive analysis of the different medical billing software available, taking into account factors such as user reviews, features, and affordability to help you make an informed decision in selecting the most popular and suitable software for your medical practice.



Medical billing software plays a crucial role in the healthcare industry by streamlining the complex process of billing and reimbursement. It assists healthcare providers in accurately and efficiently managing their revenue cycles, ensuring timely payments from insurance companies and patients. With the numerous medical billing software providers available in the market, it can be overwhelming for healthcare organizations to choose the right solution that best suits their requirements. In this comprehensive article, we will evaluate the top medical billing software providers, including the market leaders, new entrants, open-source alternatives, and specialized solutions. We will also explore the key criteria for evaluating these software solutions and provide user reviews to assist you in making an informed decision.

Top Medical Billing Software Providers


The medical billing software industry comprises a wide range of solutions catering to the diverse needs of healthcare providers. These software solutions automate and optimize various aspects of healthcare billing, such as claim submission, insurance verification, patient billing, and revenue reporting. While each software provider offers unique features and functionalities, selecting the right one requires careful consideration of your organization’s specific requirements.

Criteria for Evaluation

When evaluating medical billing software providers, several criteria should be taken into account. These include pricing, ease of use, features and functionality, customer support, and integration capabilities. Pricing is an important factor to consider as it determines the affordability and return on investment of the software solution. Ease of use ensures that the software can be easily adopted and utilized by staff members without extensive training. Features and functionality refer to the breadth and depth of functionalities offered by the software, such as electronic claims submission, reporting capabilities, and patient portal integration. Customer support is crucial in case of any technical issues or queries. Lastly, integration capabilities determine whether the software can seamlessly integrate with other essential systems in your organization, such as electronic health record (EHR) systems.


Market Leaders

Epic Systems Corporation

Epic Systems Corporation is a renowned market leader in the medical billing software industry. Their software solution, EpicCare, offers a comprehensive suite of features for healthcare organizations of all sizes. It provides robust billing functionalities, including electronic claims submission, automated denial management, and advanced reporting capabilities. Furthermore, EpicCare seamlessly integrates with their leading EHR system, EpicCare Ambulatory, allowing for efficient patient data management and billing processes.

Cerner Corporation

Cerner Corporation is another prominent player in the medical billing software market. Their software solution, Cerner Revenue Cycle Management, caters to the billing needs of healthcare organizations, regardless of their size. It offers features such as automated charge capture, revenue analytics, and proactive denial management. Cerner Revenue Cycle Management also integrates smoothly with their popular EHR system, Cerner Millennium, ensuring a seamless flow of patient and billing data.

Allscripts Healthcare Solutions

Allscripts Healthcare Solutions is a well-established provider of medical billing software. Their solution, Allscripts Practice Management, offers extensive features for billing and revenue cycle management. This software streamlines payment processes with capabilities such as electronic claims submission, automated patient eligibility verification, and real-time reporting. Allscripts Practice Management also integrates with their widely used EHR system, Allscripts Professional EHR, facilitating seamless collaboration between clinical and billing workflows.

NextGen Healthcare

NextGen Healthcare provides a comprehensive medical billing software solution known as NextGen Practice Management. It offers robust functionalities, such as automated charge capture, denial management, and contract management. NextGen Practice Management also provides advanced reporting capabilities, allowing healthcare organizations to track their financial performance effectively. The software seamlessly integrates with NextGen Healthcare’s EHR system, NextGen Ambulatory EHR, ensuring a streamlined flow of patient data for billing purposes.

Athenahealth, Inc.

Athenahealth, Inc. is a leading provider of cloud-based medical billing software. Their software solution, athenaCollector, offers an intuitive user interface combined with powerful features for billing and revenue cycle management. It automates various billing processes, such as claims submission, payment posting, and denial management. athenaCollector also includes extensive reporting capabilities and integrates seamlessly with athenahealth’s EHR system, athenaClinicals, enabling efficient collaboration between clinical and billing workflows.


New Entrants


Kareo is a new entrant in the medical billing software market that has gained popularity for its user-friendly interface and affordability. Their software solution, Kareo Billing, caters to the needs of small to medium-sized healthcare organizations. It offers features such as electronic claims submission, automated patient statements, and revenue reporting. Kareo Billing also includes a patient portal for online bill payment and appointment scheduling.


AdvancedMD is another emerging player in the medical billing software industry, focusing on providing an all-in-one solution for small to medium-sized healthcare practices. Their software solution, AdvancedMD Rhythm, combines robust billing functionalities with an integrated EHR system. It streamlines billing processes, including claims submission, denial management, and payment posting. AdvancedMD Rhythm also offers a patient portal for improved patient engagement and payment collection.


eClinicalWorks is a relatively new entrant that has gained recognition for its comprehensive EHR and medical billing software solution. Their software, eClinicalWorks Revenue Cycle Management, offers extensive billing functionalities integrated with their EHR system. It facilitates seamless claims submission, patient eligibility verification, and denial management. eClinicalWorks Revenue Cycle Management also provides reporting capabilities to monitor an organization’s financial performance.


CollaborateMD is a newcomer in the medical billing software market, focusing on delivering intuitive and affordable solutions to healthcare organizations. Their software solution, CollaborateMD Billing, offers features such as automated claims scrubbing, patient statement generation, and comprehensive reporting. CollaborateMD Billing also integrates with various EHR systems, making it accessible for healthcare organizations with different EHR preferences.


drchrono is an emerging player in the medical billing software industry, specializing in providing a comprehensive solution for ambulatory practices. Their software, drchrono EHR with Billing, combines an intuitive EHR system with billing functionalities. It offers features such as claims management, automatic coding suggestions, and real-time eligibility verification. drchrono EHR with Billing also includes a patient portal for easy communication and payment collection.


Open-source Alternatives


OpenEMR is a popular open-source medical billing software solution that is highly customizable to meet the specific needs of healthcare organizations. It offers essential billing features, such as claims creation, patient demographics management, and reporting capabilities. OpenEMR also integrates with various third-party systems, expanding its functionalities.

Oscar EMR

Oscar EMR is an open-source electronic medical record (EMR) system that includes basic medical billing functionalities. It allows healthcare organizations to submit electronic claims, manage patient billing information, and generate reports. Oscar EMR can be tailored to individual organizations’ requirements by adding specific billing modules.


FreeMED is another open-source medical billing software that provides essential features for healthcare organizations seeking a cost-effective solution. It supports claims management, patient billing, and basic reporting functionalities. FreeMED is highly customizable, allowing organizations to add specific modules or integrate with other systems as needed.


LibreHealth is an open-source health IT ecosystem that includes a medical billing component. It offers features such as billing claim creation, remittance processing, and revenue reporting. LibreHealth’s highly modular design allows for flexibility and integration with other systems, making it suitable for healthcare organizations with unique billing requirements.


OpenMRS is an open-source electronic medical record system that can be extended with add-ons to encompass billing functionalities. It allows healthcare organizations to manage patient billing transactions, generate electronic claims, and track revenue. OpenMRS’s extensive add-on repository offers options to enhance its billing capabilities.

Specialized Medical Billing Software


AdvancedMD, previously mentioned as a new entrant, also offers a specialized medical billing software solution that focuses on the unique needs of different medical specialties. These specialties include neurology, gastroenterology, dermatology, and more. AdvancedMD’s specialized software provides tailored features and workflows specific to each medical specialty, enhancing billing efficiency and accuracy.


Kareo, another new entrant in the medical billing software market, offers specialized solutions designed for specific medical specialties. Examples of these specialties include mental health, optometry, orthopedics, and more. Kareo’s specialty-specific software provides industry-specific features and customized workflows to streamline billing processes for these unique healthcare domains.


CollaborateMD, previously mentioned as a new entrant, also offers specialized medical billing software for specific specialties. Their solutions cater to specialties such as pediatrics, cardiology, urology, and more. CollaborateMD’s specialty-specific software ensures efficient billing processes tailored to the unique needs of each medical specialty.


NueMD is a specialized medical billing software provider that focuses on meeting the billing needs of mental health providers. Their software solution, NueMD Mental Health, includes features such as electronic claims submission, appointment scheduling, and patient billing statements. NueMD Mental Health streamlines billing processes specific to mental health practices, ensuring accurate and timely reimbursement.


drchrono, another provider mentioned as a new entrant, offers specialized medical billing software for various medical specialties. Their specialty-specific solutions cater to disciplines such as psychiatry, physical therapy, chiropractic, and more. drchrono’s specialized software ensures efficient billing workflows and compliance with specialty-specific requirements.

Evaluation Criteria


Pricing is a crucial consideration when evaluating medical billing software. It is important to compare the upfront costs, ongoing fees, and additional charges associated with each software solution. Some providers offer subscription-based pricing models, while others charge on a per-claim or per-user basis. Assessing the pricing structure helps healthcare organizations determine the affordability and cost-effectiveness of the software solution, aligning it with their budgetary constraints.

Ease of Use

The ease of use of the medical billing software is critical in ensuring a smooth implementation and adoption process. Software solutions should have an intuitive user interface, clearly labeled functionalities, and easily accessible support resources. Robust training and onboarding programs provided by the vendors can also contribute to the ease of use, ensuring that the software can be effectively utilized by all staff members involved in the billing process.

Features and Functionality

The features and functionalities offered by medical billing software are key factors in evaluating their suitability for an organization’s requirements. Core functionalities to consider include electronic claims submission, automated denial management, payment posting, patient billing, and reporting capabilities. Additionally, specialized features tailored to specific medical specialties, such as specialty-specific code sets and workflow templates, contribute to more efficient billing processes.

Customer Support

Responsive and reliable customer support is essential when dealing with any technical issues or inquiries related to the medical billing software. Evaluating the customer support offered by different vendors includes assessing their availability, response times, and support channels. Robust documentation, training materials, and an active user community can also contribute to a positive support experience.

Integration Capabilities

The ability of medical billing software to seamlessly integrate with other essential systems in a healthcare organization is crucial. Integration with EHR systems, practice management systems, and other third-party tools enhances workflow efficiency and reduces the duplication of efforts. It is important to evaluate the compatibility and interoperability of the software solution with existing systems, ensuring smooth data exchange and collaboration between clinical and billing workflows.


User Reviews

Positive Reviews

User reviews play a significant role in understanding the pros and cons of different medical billing software solutions. Positive reviews highlight the strengths of the software, such as user-friendly interfaces, comprehensive features, and excellent customer support. These reviews provide insights into how the software has helped healthcare organizations improve their billing processes, increase revenue, and enhance overall efficiency.

Negative Reviews

Negative reviews shed light on the limitations and areas for improvement in medical billing software solutions. These reviews address issues such as software glitches, slow response times from customer support, or complex user interfaces. Negative reviews help potential buyers understand the potential challenges or drawbacks they may encounter with certain software solutions, helping them make an informed decision.


Choosing the right medical billing software is a critical decision for healthcare organizations, as it directly impacts their revenue cycle management and overall financial performance. By evaluating the top medical billing software providers, including market leaders, new entrants, open-source alternatives, and specialized solutions, organizations can make an informed decision based on their specific requirements. It is essential to consider evaluation criteria such as pricing, ease of use, features and functionality, customer support, and integration capabilities. Additionally, user reviews provide valuable insights into the experiences of healthcare organizations using these software solutions. By considering all these factors, organizations can select the most suitable medical billing software solution to effectively streamline their billing processes and improve financial outcomes.